Vaccine approaches against HEV in pigs
Details
- Value
- £68,894
- Duration
- 2 years
- Topic
- Research and development services and related consultancy services
- Published
- 7 July 2025
- Source
- uk:find_a_tender
Tender description
This project will comprehensively test different vaccine approaches against HEV in pigs, applying a range of methods from measuring Abs to the protective signature in the liver. The hypothesis is that the vaccines may not be able to prevent infection, but to reduce HEV replication to an extend that onward transmission between pigs would no longer be possible. To that extend the approaches to investigate the above concept are as follows: · Use of an oral vaccine, a parantal vaccine, and the combination of the above – as prime/boost approach · In all cases the project will analyse the levels and quality of Abs generated. · The project will further analyse the induction of T cells by the vaccine – such analysis will be undertaken via liver and gut samples (locally) as well as systemically (in blood). The project can use flow cytometry, RNASeq or scRNASeq to demonstrate the full spectrum of functional T cells induced. The most promising candidate approach will then also be used for a challenge study. ## Contract award
Timeline
- Completed: Award published7 July 2025Current notice
- Completed: Award date7 July 2025
- Next: Contract expiry date30 September 2027in 12 months
About the buyer
Animal and Plant Health Agency (APHA) is an executive agency of the Department for Environment, Food and Rural Affairs (Defra). Defra Group Commercial handles tendering on APHA's behalf, publishing opportunities through the Find a Tender service. APHA also works on behalf of the Scottish Government and the Welsh Government. Goods, services and works are acquired by competition, with single-tender contracts limited to exceptional cases. Larger purchases need procurement strategy approval from Defra's sponsor team once APHA passes its delegated authority limit. APHA takes part in cross-government collaborative procurement projects to secure value for money.
Procurement spend from central entities makes up 66% of overall UK public spend.
Over the past 5 years, most of APHA's contract awards have been in laboratory and precision equipment, architectural and engineering services and research and development.
Relevant CPV codes
- 73000000 · Research and development services and related consultancy services
Decision makers
Connect with the people behind this procurement.
| Contact name | Job title | Phone number | Work email |
|---|---|---|---|
| Head of Procurement | +44 •••• •••••• | ••••••••@animal-and-plant-health-agency-apha.gov | |
| Commercial Director | +44 •••• •••••• | ••••••••@animal-and-plant-health-agency-apha.gov | |
| Procurement Manager | +44 •••• •••••• | ••••••••@animal-and-plant-health-agency-apha.gov | |
| Category Lead | +44 •••• •••••• | ••••••••@animal-and-plant-health-agency-apha.gov | |
| Senior Buyer | +44 •••• •••••• | ••••••••@animal-and-plant-health-agency-apha.gov | |
| Contracts Manager | +44 •••• •••••• | ••••••••@animal-and-plant-health-agency-apha.gov |
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