Closed tender

Cardiac Safety Study

Details

Published
11 September 2023
Submission
15 December 2023

Tender description

The Authority has a requirement for a preclinical in vitro cardiovascular package of work. The Authority wishes to understand the cardiovascular risk and establish QT prolongation potential for a single and multi-drug combination and fulfil the ICH S7B regulatory guidance requirements. These studies are not required to be conducted to GLP but must be in compliance with ICH S7B. A Specialist Review of relevant in house and published cardiovascular safety data is also required to provide a risk assessment and data interpretation to inform decisions on the requirement for any further cardiovascular assessments. The delivery of any recommended cardiovascular assessments may be required as a further Option. A further requirement for integrated risk assessments will be included as an Option.

Timeline

  1. Completed: Tender published11 September 2023
    Current notice
  2. Completed: Submission date15 December 2023

About the buyer

Defence Science & Technology Laboratory is the Ministry of Defence's in-house science and technology organisation, and buys as a central government agency with no preferred supplier list. R-Cloud is now the main place suppliers bid for work, including PhD funding. Framework agreements such as ASTRID and the Weapons Sector Research Framework serve government departments beyond this laboratory too.

Over the past 5 years, most of Defence Science & Technology Laboratory's contract awards have been in laboratory and precision equipment, education and training and architectural and engineering services.

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