Environmental Neurotoxicants – Advancing Understanding on the Impact of Chemical Exposure on Brain Health and Disease

Description

With this call EFSA aims to expand the use of NAMs in the area of neurotoxicity (NT) and developmental neurotoxicity (DNT) to be applied in the weight of evidence in risk assessment of pesticides. The call is also aiming at the regulatory implementation of DNT NAMs including in the call elements of laboratory transferability and reproducibility as well as DNT, NT integrated approaches for testing and assessment (IATA) using all available information. Lot 1: Lot 1 – To Generate Pesticides Data Using the DNT-IVB Type of contract: direct. Duration of tasks in direct contract: — lot 1: 36 months from kick-off meeting, — lot 2: 36 months from kick-off meeting, — lot 3: 36 months from kick-off meeting, — lot 4: 36 months from kick-off meeting. The maximum budget EFSA has available per lot is: — lot 1: EUR 1 000 000, — lot 2: EUR 500 000, — lot 3: EUR 1 500 000, — lot 4: EUR 500 000. Lot 2: Lot 2 – To Produce Transferability for the DNT IVB Type of contract: direct. Duration of tasks in direct contract: — lot 1: 36 months from kick-off meeting, — lot 2: 36 months from kick-off meeting, — lot 3: 36 months from kick-off meeting, — lot 4: 36 months from kick-off meeting. The maximum budget EFSA has available per lot is: — lot 1: EUR 1 000 000, — lot 2: EUR 500 000, — lot 3: EUR 1 500 000, — lot 4: EUR 500 000. Lot 3: Lot 3 – To Generate Pesticides/Chemicals Data for Neurotoxicity Using NAMs Type of contract: direct. Duration of tasks in direct contract: — lot 1: 36 months from kick-off meeting, — lot 2: 36 months from kick-off meeting, — lot 3: 36 months from kick-off meeting, — lot 4: 36 months from kick-off meeting. The maximum budget EFSA has available per lot is: — lot 1: EUR 1 000 000, — lot 2: EUR 500 000, — lot 3: EUR 1 500 000, — lot 4: EUR 500 000. Lot 4: Lot 4 – To Produce Collaborative AOP Informed IATA for DNT Risk Assessment of Pesticides Active Substances Type of contract: direct. Duration of tasks in direct contract: — lot 1: 36 months from kick-off meeting, — lot 2: 36 months from kick-off meeting, — lot 3: 36 months from kick-off meeting, — lot 4: 36 months from kick-off meeting. The maximum budget EFSA has available per lot is: — lot 1: EUR 1 000 000, — lot 2: EUR 500 000, — lot 3: EUR 1 500 000, — lot 4: EUR 500 000.