Contract for a Multi-Electrode Array (MEA) System for measuring cellular electrical activity

Description

The proposal surrounding this Higher Education Research Capital (HERC) Funding 2023-24 from the Higher Education Funding Council for Wales (HEFCW), aims to elucidate fundamental mechanisms of underlying neurodegenerative disorders, and specifically to determine the role that abundant brain lipids called plasmalogens play in supporting synaptic transmission. Whilst there are no effective treatments for patients with cognitive impairment, dementia, or Alzheimer’s Disease (AD) and none of the available is targeted at preserving synapse integrity and function, this study addresses the role of plasmalogens in synaptic assembly and maintenance