Low-flow liquid chromatography ultrahigh-resolution mass spectrometry platform

Description

DTU Sustain is working with environmental forensics and metabolomic investigations to study the fate and occurrence of chemicals and small molecules dispersed into the environment. To be able to make these investigations, DTU wants to procure a low-flow liquid chromatography ultrahigh-resolution mass spectrometry platform, capable of characterizing small molecules with collisional dissociation and laser-based ultraviolet-photodissociation (UVPD) for multi-stage molecular fragmentation (MSn) in liquid chromatography time scale. The mass spectrometer platform must have two independent mass detectors, and capable of resolving very complex molecular mixtures to improve unknown chemical characterization with fine isotope detection at one million in mass resolution (at mass-to-charge 200) or higher. The liquid chromatography system must be able to make chromatographic separations of complex mixtures at low-flow conditions (10-100 nano-liters per minute) and seamlessly integrated with nanoelectrospray ionization and controlled, jointly with themass spectrometer, within the same software environment.