Variable Field NMR Spectrometer

Description

The National Physical Laboratory [NPL] requirement is for a Variable Field Nuclear Magnetic Resonance (NMR) spectrometer for the measurement of T1, T2, T2*, apparent diffusion coefficient, and proton density fat fraction in the liquid state. The purpose is to enable traceable, high-precision measurements of these measurands, to allow for the development of metrological standards for Magnetic Resonance Imaging (MRI). The ITT is separated into two components; the Instrument, and the Facility. We welcome tenders for either or both. The Instrument should comprise an NMR Spectrometer, with all associated componentry (e.g., the magnet, console, probe(s), temperature control system, shims, and workstation). This should be a fully programmable spectrometer, with the capability to measure the NMR spectra of chosen samples using appropriate pulse sequences and export the resulting data to an appropriate data storage or archival facility. The magnetic field should be variable, with the ability to change the field on a monthly basis. The magnetic field should be able to reach clinically relevant MRI fields (e.g., 1.5, 2.9, 3.0, 5.0, 7.0 T), and have the capability for lower field strengths down to 0.1 T or lower. The spectrometer should be compatible with the existing equivalent facility at NIST Boulder. The Facility should comprise a ‘room-within-a-room’ NMR Laboratory, including a dedicated power supply. This Facility should be shielded from RF, magnetic, and vibrational interference sufficiently such that a future MRI scanner could be installed adjacent. It should include temperature regulation to ensure a set point of 20C +- 0.5C is always maintainable, with temperature, humidity, and pressure monitoring. The Facility should be access controlled in a manner compatible with the NPL access control system, and include provision for lone working, and appropriate safety features. It must follow all necessary safety regulations, including with regards to signage.