Laboratory, optical and precision equipments (excl. glasses)

Description

DTU is currently building a big fermentation infrastructure, which, in the long run, will accommodate many fermenters, from bench to pilot-scale, carrying out a wide array of biological transformations. DTU needs to work in parallel with fermentation systems that are controlled automatically and independently from each other and have the possibility to accommodate fermentations with different types of microbes and substrates (including gasses) and a very broad variety of operation conditions. Within this frame we are purchasing 2 fermentation systems with stainless steel vessels and 6 fermentation systems with glass vessels. We are currently building a big fermentation infrastructure, which, in the long run, will accommodate many fermenters, from bench to pilot-scale, carrying out a wide array of biological transformations. So we would like to be able to work in parallel with fermentation systems that are controlled automatically and independently from each other and have the possibility to accommodate fermentations with different types of microbes and substrates (including gasses) and a very broad variety of operation conditions. Within this frame we are purchasing 2 fermentation systems with stainless steel vessels. We concluded that Sartorius is the only fermentation systems provider currently available in the market worldwide that can fulfill the following requirements: — working volume between 3L and 10L, — designed for in-situ sterilization, — baffles must be included, — harvest pipe that reaches the bottom of the vessel, — sampling system for sterile sampling, — aeration through ring sparger, — 3 x Rushton Turbine Impellers for each vessel, — working temperature from 10 oC to 80 oC, — agitation rate from 0-1500 rpm, — measurement and control of pO2, pH and Redox, — integrated pumps for Acid/Base, — level Control with integrated pump, — 2 pumps for substrate, — one of the substrate pumps should be used in the redox controller as the reducing agent, — one of the substrate pumps should be used in the redox controller as the oxidizing agent, — overpressure measurement control should be included, — MFC for Air/O2 with range from 0-20 L/min controlled by pO2-value, — MFC for CO2 with range from 0-20 L/min manually controlled, — MFC for premixed mixture of CO, CO2, H2 and CH4 with range from 0-100 ccm/min manu-ally controlled. MFC should be ATEX, — MFC for H2 with range from 0-100 ccm/min manually controlled. MFC should be ATEX, — a solution with hollowfiber or similar functionality for removing bacteria free media during the fermentation should be included, — software for data collection and control should be included, — The fermenters will be placed in different rooms so they should run completely independent of each other. We are currently building a big fermentation infrastructure, which, in the long run, will accommodate many fermenters, from bench to pilot-scale, carrying out a wide array of biological transformations. So we would like to be able to work in parallel with fermentation systems that are controlled automatically and independently from each other and have the possibility to accommodate fermentations with different types of microbes and substrates (including gasses) and a very broad variety of operation conditions. Within this frame we are purchasing 2 fermentation systems with stainless steel vessels. We concluded that Sartorius is the only fermentation systems provider currently available in the market worldwide that can fulfill the following requirements: — working volume between 3L and 10L, — designed for in-situ sterilization, — baffles must be included, — harvest pipe that reaches the bottom of the vessel, — sampling system for sterile sampling, — aeration through ring sparger, — 3 x Rushton Turbine Impellers for each vessel, — working temperature from 10 oC to 80 oC, — agitation rate from 0-1500 rpm, — measurement and control of pO2, pH and Redox, — integrated pumps for Acid/Base, — level Control with integrated pump, — 2 pumps for substrate, — one of the substrate pumps should be used in the redox controller as the reducing agent, — one of the substrate pumps should be used in the redox controller as the oxidizing agent, — overpressure measurement control should be included, — MFC for Air/O2 with range from 0-20 L/min controlled by pO2-value, — MFC for CO2 with range from 0-20 L/min manually controlled, — MFC for premixed mixture of CO, CO2, H2 and CH4 with range from 0-100 ccm/min manu-ally controlled. MFC should be ATEX, — MFC for H2 with range from 0-100 ccm/min manually controlled. MFC should be ATEX, — a solution with hollowfiber or similar functionality for removing bacteria free media during the fermentation should be included, — software for data collection and control should be included, — the fermenters will be placed in different rooms so they should run completely independent of each other.