Freeze Dryer Phase II
Published
Value
Description
To replace the PLC hardware for CS15 and CS150 with up-to-date equivalents that align with the Schneider upgrade path.<br/>To replace the HMI hardware for CS15 and CS150 with up-to-date equivalents that align with those used in Phase 1.<br/>To recreate the functionality of CS15 and CS150 PLCs like-for-like following the Schneider upgrade path.<br/>To re-create the CS15 and CS150 HMIs and allow for development of further requirement defined in collaboration with the MHRA. Lot 1: To replace the PLC hardware for CS15 and CS150 with up-to-date equivalents that align with the Schneider upgrade path.<br/>To replace the HMI hardware for CS15 and CS150 with up-to-date equivalents that align with those used in Phase 1.<br/>To recreate the functionality of CS15 and CS150 PLCs like-for-like following the Schneider upgrade path.<br/>To re-create the CS15 and CS150 HMIs and allow for development of further requirement defined in collaboration with the MHRA.<br/>1. Project Definition<br/>– All parties to agree scope and ensure that everything is available for project commencement. <br/>– MHRA to provide any existing software backups (PLC / SCADA source code).<br/>– For software that is not available (such as the HMI), the supplier is expected to work with the MHRA to develop the requirements for the HMI.<br/>– Both parties to agree deliverable format (e.g. schematic updates).<br/>2. Part Selection<br/>– Using the information gathered at the project definition stage, the supplier will select updated hardware and software packages for the PLCs, HMIs, SCADAs, data historian and anti-virus software.<br/>3. Electrical Design<br/>– With appropriate parts selected, the supplier will need to assess how the electrical design will be impacted by the proposed changes.<br/>– These impacts should be minimised wherever possible.<br/>– However, if changes are required, the supplier will need to modify any schematics while aligning with appropriate standards.<br/>4. Software Development<br/>– Software development for the PLC, HMI, SCADA and Data Historian can be started following on from part selection.<br/>– This will require the supplier to migrate functionality where possible.<br/>– Where the code cannot be migrated, the functionality will need to be replicated.<br/>– The HMI should be re-built to meet the requirements based on existing SCADA screens and workshops held with MHRA operators.<br/>5. FAT (Factory Acceptance Testing)<br/>– The control cabinets and associated hardware shall not be moved from the MHRA facility.<br/>– FAT is expected to test as much of the new software and hardware as possible without replicating site hardware.<br/>6. Plant Upgrades<br/>– This will include the MHRA ensuring that appropriate ethernet connection shall be made available and new virtual machines are available.<br/>7. SAT (Site Acceptance Testing)<br/>– SAT will need to be staggered to reduce any concurrent downtime to the freeze dryers. This will require testing and commissioning only one freeze dryer at a time.<br/>– SAT is expected to test all software and hardware associated with the replacement hardware and the existing site hardware.<br/>8. On-going contract Support<br/>– Support is expected for the warranty of the system following from SAT and moving onto general support for the years following the warranty end.<br/>– During these periods, the supplier is expected to ensure that recommend patches will not cause un-planned downtime.<br/>– It is desired that the supplier can also provide support for the Phase 1 system (CS100). Lot 1: To replace the PLC hardware for CS15 and CS150 with up-to-date equivalents that align with the Schneider upgrade path.<br/>To replace the HMI hardware for CS15 and CS150 with up-to-date equivalents that align with those used in Phase 1.<br/>To recreate the functionality of CS15 and CS150 PLCs like-for-like following the Schneider upgrade path.<br/>To re-create the CS15 and CS150 HMIs and allow for development of further requirement defined in collaboration with the MHRA.<br/>1. Project Definition<br/>– All parties to agree scope and ensure that everything is available for project commencement. <br/>– MHRA to provide any existing software backups (PLC / SCADA source code).<br/>– For software that is not available (such as the HMI), the supplier is expected to work with the MHRA to develop the requirements for the HMI.<br/>– Both parties to agree deliverable format (e.g. schematic updates).<br/>2. Part Selection<br/>– Using the information gathered at the project definition stage, the supplier will select updated hardware and software packages for the PLCs, HMIs, SCADAs, data historian and anti-virus software.<br/>3. Electrical Design<br/>– With appropriate parts selected, the supplier will need to assess how the electrical design will be impacted by the proposed changes.<br/>– These impacts should be minimised wherever possible.<br/>– However, if changes are required, the supplier will need to modify any schematics while aligning with appropriate standards.<br/>4. Software Development<br/>– Software development for the PLC, HMI, SCADA and Data Historian can be started following on from part selection.<br/>– This will require the supplier to migrate functionality where possible.<br/>– Where the code cannot be migrated, the functionality will need to be replicated.<br/>– The HMI should be re-built to meet the requirements based on existing SCADA screens and workshops held with MHRA operators.<br/>5. FAT (Factory Acceptance Testing)<br/>– The control cabinets and associated hardware shall not be moved from the MHRA facility.<br/>– FAT is expected to test as much of the new software and hardware as possible without replicating site hardware.<br/>6. Plant Upgrades<br/>– This will include the MHRA ensuring that appropriate ethernet connection shall be made available and new virtual machines are available.<br/>7. SAT (Site Acceptance Testing)<br/>– SAT will need to be staggered to reduce any concurrent downtime to the freeze dryers. This will require testing and commissioning only one freeze dryer at a time.<br/>– SAT is expected to test all software and hardware associated with the replacement hardware and the existing site hardware.<br/>8. On-going contract Support<br/>– Support is expected for the warranty of the system following from SAT and moving onto general support for the years following the warranty end.<br/>– During these periods, the supplier is expected to ensure that recommend patches will not cause un-planned downtime.<br/>– It is desired that the supplier can also provide support for the Phase 1 system (CS100).
Timeline
Publish date
23 days ago
Close date
16 days ago
Buyer information
Medicines and Healthcare products Regulatory Agency
- Contact:
- Jonathon Liam Moloney
- Email:
- jonathon.moloney@mhra.gov.uk
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